CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,802 enrolled
Drug / intervention
Combined epidural-general anesthesia +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03335826
NCT03335826N/ACompleted
CompareCT.gov

Impact of Epidural Anesthesia-analgesia on Long-term Outcomes in Elderly Patients After Surgery: 5-year Follow-up of a Multicenter Randomized Controlled Trial

Peking University First Hospital·interventional·Posted Nov 8, 2017·Updated Apr 14, 2020

In Brief

A clinical study evaluating Combined epidural-general anesthesia and General anesthesia for Elderly Patients and 4 related conditions. Completed, enrolled 1,802 participants across 5 sites.

Detailed Summary

Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure. The outcomes after surgery are mainly dependent on the balance between the immune function of the body and the invasiveness of residual cancer. Preclinical and retrospective studies suggest that anaesthetic techniques and drugs may affect the long-term outcomes in patients undergoing cancer surgery. The investigators hypothesize that epidural anesthesia-analgesia may improve long-term survival in the elderly who undergo major surgery for cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsElderly Patients, Solid Organ Cancer, Surgical Resection, Epidural Anesthesia, Long-term Outcome
CountriesChina
CollaboratorsPeking University People's Hospital, Peking University Third Hospital, Beijing Hospital, Beijing Shijitan Hospital, Capital Medical University

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedNov 8, 2017
Enrollment StartAug 1, 2017
Primary CompletionSep 30, 2019
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 8.7 years ago

Interventions

Combined epidural-general anesthesiaprocedure

Combined epidural-general anesthesia and postoperative epidural analgesia.

General anesthesiaprocedure

General anesthesia and postoperative intravenous analgesia.