CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 205 enrolled
Drug / intervention
Cabiralizumab +8 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03336216
NCT03336216Phase 2Completed

A Phase 2 Study of Cabiralizumab (BMS-986227, FPA008) Administered in Combination With Nivolumab (BMS-936558) With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

Bristol-Myers Squibb·interventional·Posted Nov 8, 2017·Updated Jul 23, 2024

In Brief

A Phase 2 clinical trial evaluating Cabiralizumab, Nab-paclitaxel, and 7 other interventions for Advanced Pancreatic Cancer. Completed, enrolled 205 participants across 41 sites in 11 countries.

Detailed Summary

The purpose of this study is to determine whether an investigational immuno-therapy, cabiralizumab in combination with nivolumab, with or without chemotherapy, is effective for the treatment of advanced pancreatic cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Denmark, Germany, Italy, Japan, South Korea, Spain, Switzerland, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedNov 8, 2017
Enrollment StartDec 18, 2017
Primary CompletionJun 1, 2023
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 8.7 years ago

Interventions

Cabiralizumabbiological

specified dose on specified days

Nab-paclitaxeldrug

specified does on specified days

Onivydedrug

specified dose on specified days

Nivolumabbiological

specified dose on specified days

Fluorouracildrug

specified dose on specified days

Gemcitabinedrug

specified dose on specified days

Oxaliplatindrug

specified dose on specified day

Leucovorindrug

Specified dose on specified days

Irinotecan Hydrochloridedrug

Specified dose on specified days