CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 230 enrolled
Drug / intervention
Antimicrobial Barrier Dressing +1 morecombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03345771
NCT03345771Phase 3Completed

Antimicrobial Barrier Dressing Versus Closed-incision Negative Pressure Therapy in the Obese Primary Total Joint Arthroplasty

NYU Langone Health·interventional·Posted Nov 17, 2017·Updated Apr 22, 2022

In Brief

A Phase 3 clinical trial evaluating Antimicrobial Barrier Dressing and Negative Pressure Wound Therapy (NPWT) for Osteoarthritis. Completed, enrolled 230 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether an occlusive antimicrobial barrier dressing or portable negative pressure wound dressing is superior in preventing wound complications and infection rates in obese patients undergoing total joint arthroplasty (TJA). Approximately 240 subjects (120 for total knee arthroplasty and 120 for total hip arthroplasty) will be enrolled to evaluate the outcomes associated with silver impregnated dressings and negative pressure wound therapy (NPWT) in treating this subset of patients and analyze the cost benefit of each.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedNov 17, 2017
Enrollment StartNov 13, 2017
Primary CompletionApr 1, 2021
Study CompletionJun 1, 2021
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 8.6 years ago

Interventions

Antimicrobial Barrier Dressingcombination

Ionic Silver is a soft, nonwoven pad or ribbon that features the gelling benefits of Hydrofiber technology plus antimicrobial ionic silver.

Negative Pressure Wound Therapy (NPWT)device

PICO provides suction known as negative Pressure wound Therapy (NPWT) which draws out excess fluid from a wound and protects the injured area from getting dirty to ultimately help promote healing. PICO consists of an nPwT pump connected to an absorbent gentle adhesive dressing