CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 50 enrolled
Drug / intervention
Ropivacaine +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03353233
NCT03353233Phase 4Completed

Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.

Duke University·interventional·Posted Nov 27, 2017·Updated Dec 21, 2021

In Brief

A Phase 4 clinical trial evaluating Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, and 1 other intervention for Knee Osteoarthritis and 4 related conditions. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee to aid in physical therapy after surgery. The iPACK technique uses a numbing solution (local anesthetics) that is injected behind the knee to reduce pain and to help straighten the knee. This block may affect movement in the leg and make the legs weak, but thing is rare. A few institutions use the iPACK block for patients having total knee replacements, with the hope of providing good pain relief combined with improved mobility after surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedNov 27, 2017
Enrollment StartMay 3, 2018
Primary CompletionJan 22, 2021
Study CompletionJan 23, 2021
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 8.6 years ago

Interventions

Ropivacainedrug

Local anesthetic (numbing drug)

Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Blockprocedure

An ultrasound guided nerve block using a numbing medication called ropivacaine that numbs the nerves to the back of the knee.

Salinedrug

An ultrasound guided nerve block using a medication that does NOT numb the nerve called saline, or salt water.