CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 406 enrolled
Drug / intervention
efpeglenatide (SAR439977) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03353350
NCT03353350Phase 3Completed

A 56-week, Multicenter, Double-blind, Placebo-controlled, Randomized Study to Evaluate the Efficacy and Safety of Efpeglenatide Once Weekly in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise

Hanmi Pharmaceutical Company Limited·interventional·Posted Nov 27, 2017·Updated Jan 18, 2022

In Brief

A Phase 3 clinical trial evaluating efpeglenatide (SAR439977) and placebo for Type 2 Diabetes Mellitus. Completed, enrolled 406 participants across 54 sites in 5 countries.

Detailed Summary

Primary Objective: To demonstrate the superiority of once weekly injection of efpeglenatide in comparison to placebo in glycated hemoglobin (HbA1c) change in participants with T2DM (Type 2 Diabetes Mellitus) inadequately controlled with diet and exercise. Secondary Objectives: * To demonstrate the superiority of once-weekly injection of efpeglenatide in comparison to placebo on glycemic control * To demonstrate the superiority of once-weekly injection of efpeglenatide in comparison to placebo on body weight * To evaluate the safety of once-weekly injection of efpeglenatide

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Poland, Ukraine, United Kingdom, United States
CollaboratorsSanofi

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedNov 27, 2017
Enrollment StartDec 5, 2017
Primary CompletionJan 29, 2020
Study CompletionSep 7, 2020
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 8.6 years ago

Interventions

efpeglenatide (SAR439977)drug

Pharmaceutical form: solution for injection Route of administration: subcutaneous

placebodrug

Pharmaceutical form: solution for injection Route of administration: subcutaneous