At a glance
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Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
In Brief
A Phase 3 clinical trial evaluating Dexamethasone, Laboratory Biomarker Analysis, and 5 other interventions for Breast Carcinoma. Completed, enrolled 1,363 participants across 18 sites.
Detailed Summary
This randomized phase III trial studies how well netupitant/palonosetron hydrochloride and dexamethasone with prochlorperazine or olanzapine work compared to netupitant/palonosetron hydrochloride and dexamethasone in improving chemotherapy-induced nausea and vomiting in patients with breast cancer. Antiemetic drugs, such as prochlorperazine and olanzapine, may help lessen nausea and vomiting in patients with breast cancer treated with chemotherapy.
Study Details
Timeline
Interventions
Given PO
Correlative studies
Given PO
Given PO
Given PO
Given PO
Ancillary studies