CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 356 enrolled
Drug / intervention
BMS-986249 +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03369223
NCT03369223Phase 2Completed

A Phase 1/2 First-in-Human Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors

Bristol-Myers Squibb·interventional·Posted Dec 11, 2017·Updated Nov 18, 2025

In Brief

A Phase 2 clinical trial evaluating BMS-986249, Nivolumab, and 1 other intervention for Advanced Cancer. Completed, enrolled 356 participants across 45 sites in 11 countries.

Detailed Summary

The purpose of this study is to determine whether BMS-986249 both by itself and in combination with Nivolumab is safe and tolerable in the treatment of advanced solid tumors

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdvanced Cancer
CountriesArgentina, Australia, Canada, Chile, Finland, Germany, Italy, Poland, Romania, Spain, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedDec 11, 2017
Enrollment StartDec 6, 2017
Primary CompletionNov 7, 2024
TodayJul 2, 2026
Enrollment to primary: 6.9 yearsPosted 8.6 years ago

Interventions

BMS-986249biological

Specified dose on specified days

Nivolumabbiological

Specified dose on specified days

Ipilimumabbiological

Specified dose on specified days