CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 88 enrolled
Drug / intervention
Total coumarin (TC) cream +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03372811
NCT03372811Phase 2Completed

A Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase IIb Clinical Trial (PLANTCOAT-IIb) to Evaluate the Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris

Psoriasis Research Institute of Guangzhou·interventional·Posted Dec 14, 2017·Updated Mar 25, 2026

In Brief

A Phase 2 clinical trial evaluating Total coumarin (TC) cream and Vehicle for Psoriasis Vulgaris and Topical Administration. Completed, enrolled 88 participants across 2 sites.

Detailed Summary

A Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of a Botanical Total Coumarin Cream (TC) in Treating Patients with Psoriasis Vulgaris

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 14, 2017
Enrollment StartJun 11, 2015
Primary CompletionMar 14, 2018
Study CompletionJun 30, 2018
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 8.5 years ago

Interventions

Total coumarin (TC) creamdrug

A well-characterized botanical drug for the topical treatment of psoriasis vulgaris. The drug has been approved by the NMPA in China and has obtained an NDA following multiple clinical trials spanning phases I-III in large cohorts.

Vehicledrug

Vehicle