CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Standard EAA +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03372928
NCT03372928N/ACompleted

The Effects of Varying Essential Amino Acid Intakes on Resting and Post-exercise Skeletal Muscle and Whole-body Protein Kinetics During Negative Energy Balance

United States Army Research Institute of Environmental Medicine·interventional·Posted Dec 14, 2017·Updated Nov 20, 2020

In Brief

A clinical study evaluating Standard EAA and High EAA for Muscle Protein Synthesis and Whole-body Protein Balance. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The amount of essential amino acids (EAA) necessary to maximally stimulate muscle protein synthesis and optimize whole-body net protein balance during caloric deprivation has not been determined. This study will address that gap in knowledge by examining the resting and post-exercise muscle and whole-body protein kinetic responses to ingesting varying amounts of EAA after a 5 day period of negative energy balance. This study will provide the initial evidence to support the development of a recovery-based food product for military combat rations.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedDec 14, 2017
Enrollment StartSep 1, 2018
Primary CompletionMar 20, 2019
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 8.5 years ago

Interventions

Standard EAAdietary

EAA provided relative to body mass at a standard dose (0.10 g/kg) during energy deprivation

High EAAdietary

EAA provided relative to body mass at a high dose (0.30 g/kg) during energy deprivation