CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 181 enrolled
Drug / intervention
mRNA-1647 +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03382405
NCT03382405Phase 1Completed

A Phase 1, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus Vaccines mRNA-1647 and mRNA-1443 When Administered to Healthy Adults

ModernaTX, Inc.·interventional·Posted Dec 22, 2017·Updated Jan 15, 2021

In Brief

A Phase 1 clinical trial evaluating mRNA-1647, mRNA-1443, and 1 other intervention for Cytomegalovirus Infection. Completed, enrolled 181 participants across 4 sites.

Detailed Summary

This clinical study will assess the safety, reactogenicity and immunogenicity of mRNA-1647 and mRNA-1443 cytomegalovirus vaccines in healthy adults

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
201820192020202120222023202420252026
First PostedDec 22, 2017
Enrollment StartNov 13, 2017
Primary CompletionOct 28, 2020
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 8.5 years ago

Interventions

mRNA-1647biological

Escalating dose levels

mRNA-1443biological

Escalating dose levels

Placeboother

Saline