At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model
In Brief
A Phase 3 clinical trial evaluating 0 ppm F (placebo, negative control), 250 ppm F as NaF (dose-response control), and 2 other interventions for Caries. Completed, enrolled 28 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 500 and 1100 ppm fluoride of our existing in situ model involving the use of human enamel specimens placed in the buccal flange area of the subjects partial denture with the modified model involving placement of bovine enamel specimens in a denture tooth location.
Study Details
Timeline
Interventions
Each subject will use this product during one of the four treatment periods in the crossover study design.
Each subject will use this product during one of the four treatment periods in the crossover study design.
Each subject will use this product during one of the four treatment periods in the crossover study design.
Each subject will use this product during one of the four treatment periods in the crossover study design.