CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 68 enrolled
Drug / intervention
EDP-305 1 mg +2 moredrug
Likely dose
EDP-305 1 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03394924
NCT03394924Phase 2Completed

A Phase 2 Dose Ranging, Randomized, Double Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis (PBC) With or Without an Inadequate Response to Ursodeoxycholic Acid (UDCA)

Enanta Pharmaceuticals, Inc·interventional·Posted Jan 9, 2018·Updated May 18, 2021

In Brief

A Phase 2 clinical trial evaluating EDP-305 1 mg, EDP-305 2.5 mg, and 1 other intervention for Primary Biliary Cholangitis. Completed, enrolled 68 participants across 86 sites in 10 countries.

Detailed Summary

A randomized, double-blind study to assess the safety, tolerability, PK and efficacy of EDP-305 in subjects with primary biliary cholangitis

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Belgium, Canada, France, Germany, Netherlands, Spain, United Kingdom, United States

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedJan 9, 2018
Enrollment StartDec 27, 2017
Primary CompletionDec 19, 2019
Study CompletionJan 16, 2020
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 8.5 years ago

Interventions

EDP-305 1 mgdrug

Two tablets daily for 12 weeks

EDP-305 2.5 mgdrug

Two tablets daily for 12 weeks

Placebodrug

Two tablets daily for 12 weeks