CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
i-PRF +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03399422
NCT03399422N/ACompleted

Evaluation the Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Upper Canine Retraction and the Levels of Acceptance and Discomfort

Damascus University·interventional·Posted Jan 16, 2018·Updated Feb 5, 2020

In Brief

A clinical study evaluating i-PRF and canine retraction for Malocclusion, Angle Class II, Division 1. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary arch at the first premolar region , and the other side served as the control. canine retraction will be initiated after completion of the leveling and alignment phase via closed nickel-titanium coil springs applying 150 g of force per side , soldered transpalatal arch will be used as an anchor unit. Pre- and post distalization dental casts will be evaluated to study rate of canine distalization, over a follow-up period until a Class I canine relationship will be achieved. The levels of Pain and discomfort will be monitored using a questionnaire with a VAS scale administered three times during the first day after prf injection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSyria
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJan 16, 2018
Enrollment StartAug 20, 2017
Primary CompletionAug 1, 2018
Study CompletionAug 1, 2019
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 8.5 years ago

Interventions

i-PRFbiological

i-PRF (injectable platelet rich fibrin) assisted upper canine retraction

canine retractionprocedure

upper canine retraction will be performed in one side of patients with Class II Division 1 malocclusion patients requiring therapeutic extraction of the maxillary first premolars