At a glance
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Peripheral Nerve Blocks for Upper Leg Amputations
In Brief
A Phase 4 clinical trial evaluating Peripheral nerve block, Intravenous Sedatives, and 2 other interventions for Peripheral Vascular Diseases and 4 related conditions. Completed, enrolled 30 participants across 1 site.
Detailed Summary
Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).
Study Details
Timeline
Interventions
All enrollees will have ultrasound-guided femoral and sciatic nerve blocks placed per current practice at research site. Single-injection obturator and lateral femoral cutaneous nerve blocks will also be performed.
Intravenous sedation using propofol or dexmedetomidine will be administered.
After administration of intravenous sedation, lateral femoral cutaneous and obturator nerve blocks (in addition to the femoral and sciatic catheters) will be performed under ultrasound guidance.
After administration of intravenous sedation, lateral femoral cutaneous and obturator nerve blocks (in addition to the femoral and sciatic catheters) will be performed under ultrasound guidance.