CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,227 enrolled
Drug / intervention
Foley bulb plus Oral Misoprostol +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03407625
NCT03407625N/ACompleted

Foley Bulb With Oral Misoprostol Versus Oral Misoprostol for Induction of Labor: A Cluster Randomized Trial

University of Texas Southwestern Medical Center·interventional·Posted Jan 23, 2018·Updated Nov 4, 2020

In Brief

A clinical study evaluating Foley bulb plus Oral Misoprostol and Oral Misoprostol for Pregnancy and Labor, Induced. Completed, enrolled 2,227 participants across 1 site.

Detailed Summary

Induction of labor is associated with increased cesarean delivery rates, particularly in women with an unfavorable cervix. Both pharmacologic and mechanical methods are utilized for cervical ripening and labor induction. Evidence on the safety and effectiveness of various mechanical and pharmacologic methods of cervical ripening and labor induction is abundant, and yet the majority of clinical trials evaluate time to delivery, rather than mode of delivery. This is a prospective, cluster-randomized clinical trial to compare a standard method of induction at our institution (oral misoprostol) with an alternative, commonly used combination method of oral misoprostol and transcervical foley bulb in women with term pregnancies requiring induction of labor.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJan 23, 2018
Enrollment StartJan 1, 2018
Primary CompletionMay 13, 2019
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 8.4 years ago

Interventions

Foley bulb plus Oral Misoprostolother

Although labeled "experimental" for comparison purposes, this is not an experimental intervention, as the method is a currently accepted standard of care for cervical ripening and labor induction in the United States.

Oral Misoprostolother

Patients will receive standard oral misoprostol 100mcg according to current Labor Induction Protocol.