At a glance
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An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia
In Brief
A Phase 3 clinical trial evaluating evinacumab for Homozygous Familial Hypercholesterolemia. Completed, enrolled 116 participants across 38 sites in 12 countries.
Detailed Summary
The primary objectives of the study are: * To evaluate the long-term safety and tolerability of evinacumab in patients with Homozygous Familial Hypercholesterolemia (HoFH) * To evaluate the long-term safety and tolerability of evinacumab in adolescent patients with HoFH The secondary objectives of the study are: * To evaluate the effect of evinacumab on lipid parameters in patients with HoFH * To evaluate the effect of evinacumab on lipid parameters in adolescent patients with HoFH * To evaluate the potential development of anti-evinacumab antibodies
Study Details
Timeline
Interventions
Intravenous (IV) administration