At a glance
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A Single Arm Study of 6-Months Neoadjuvant Apalutamide Prior to Radical Prostatectomy in Intermediate Risk Patients to Reduce the Frequency of Pathologic Features That Drive Post-Operative Radiation Therapy
In Brief
A Phase 2 clinical trial evaluating Apalutamide, Quality-of-Life Assessment, and 1 other intervention for Prostate Adenocarcinoma and Stage IIB Prostate Cancer AJCC v8. Active but no longer recruiting, targeting 45 participants across 1 site.
Detailed Summary
This phase II trial studies how well apalutamide works in treating patients with prostate cancer before radical prostatectomy. Androgen can cause the growth of prostate cancer cells. Hormone therapy using apalutamide may fight prostate cancer by lowering the amount of androgen the body makes and may make it less likely for patients to receive radiation therapy after surgery.
Study Details
Timeline
Interventions
Given PO
Ancillary studies
Undergo radical prostatectomy