CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Healthy Control +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03414086
NCT03414086N/ACompleted

Predictor of Clinical Response to Acthar in Myositis: Phase II of Acthar Clinical Trial

University of Pittsburgh·observational·Posted Jan 29, 2018·Updated Aug 9, 2022

In Brief

An observational study evaluating Healthy Control and Myositis in Remission for Myositis and 2 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Comparing the clinical effects of Acthar Gel before and after treatment and compare it to patients with inactive disease.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJan 29, 2018
Enrollment StartNov 6, 2017
Primary CompletionJul 30, 2022
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 8.4 years ago

Interventions

Healthy Controlother

Ten healthy adult patients evaluating serum, PBMC's, and RNA.

Myositis in Remissionother

Ten patients (four who have polymyositis, six dermatomyositis) from our database who are followed in the Myositis Center. We will collect serum, PBMC's, and RNA samples will be obtained at baseline and at six months. Remission is defined as a global myositis disease activity score less than or equal to 1 on the MDAAT assessments with no new immunosuppressive drug or glucocorticoid use and no increase in dose of either in the preceding year.