CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 54 enrolled
Drug / intervention
Beverage consumption +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03416088
NCT03416088N/ACompleted

The Influence of Daily Activities on Retinal Microcirculation in Normal Adults

Jiannan Huang·interventional·Posted Jan 30, 2018·Updated Apr 17, 2025

In Brief

A clinical study evaluating Beverage consumption, Daily reading, and 1 other intervention for Retinal Microcirculation Disorder. Completed, enrolled 54 participants across 1 site.

Detailed Summary

The daily behaviors such as drinking coffee, wine, reading, exercise and body postural changes may have influence on the function or morphology of the retinal microcirculation in healthy people.A recent study found that the fingertips microvascular bed constricted obviously after the intake of a cup of coffee with caffeine, it significantly reduced blood flow to the fingers; Long reading of electronic products can induce significant dry eye symptoms, affect visual quality, and cause asthenopia. Microcirculation is critical for regulating vascular resistance and blood flow in organs. Fundus blood vessels is the only visible microvascular in vivo, its morphology and function changes not only associated with eye disease, but also with cardiovascular and cerebrovascular diseases. Optical coherence tomography angiography (OCTA) is a new technique which could acquire blood flow information in a non-invasive way without the use of dye. Magnetic resonance imaging (MRI) can quantitatively evaluation of cerebral blood flow and retina-choroid blood flow using the noninvasive arterial spin labeling technique in a large field of view (FOV) without depth limitations.The study tried to detect the influence of daily behaviors such as drinking coffee, red wine, reading , exercise, etc. on the retinal microcirculation with OCTA and MRI, and provide reference for health behaviors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJan 30, 2018
Enrollment StartMay 1, 2017
Primary CompletionOct 31, 2020
Study CompletionDec 31, 2020
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 8.4 years ago

Interventions

Beverage consumptionbehavioral

The participants drink 300ml wine (alcohol concentration:12.5%)or 300ml coffee (caffeine concentration 72 mg), or water.

Daily readingbehavioral

Reading paper books, playing video games with mobile phones, or non-reading for 8 hours.

Body motionbehavioral

Exercise or body postural changes