At a glance
ClinicalIndex Comparison RecordN/ACompleted· 100 enrolled
Drug / intervention
Nitrous Oxidedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Nitrous Oxide Added at the End of Sevoflurane Anesthesia on Recovery and Postoperative Nausea and Vomiting - a Randomized Clinical Trial (SEVONATE)
In Brief
A clinical study evaluating Nitrous Oxide for Elective Surgical Procedures and 4 related conditions. Completed, enrolled 100 participants across 1 site.
Detailed Summary
Addition of nitrous oxide N2O towards the end of prolonged isoflurane anesthesia hastens patients recovery. The hypothesis is that the addition of N2O at the end of prolonged sevoflurane anaesthesia also hastens early recovery without increasing the frequencies and intensity of PONV and improves quality of recovery.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsElective Surgical Procedures, Laparoscopy, Laparotomy, Anesthesia, General, Anesthesia Recovery Period
CountriesCroatia
Collaborators--
Timeline
N/ACompletedFinished
201820192020202120222023202420252026
First PostedFeb 2018
Enrollment StartFeb 2018
Primary CompletionJul 2021
Study CompletionJul 2021
TodayJul 2026
First PostedFeb 5, 2018
Enrollment StartFeb 7, 2018
Primary CompletionJul 10, 2021
Study CompletionJul 25, 2021
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 8.4 years ago
Interventions
Nitrous Oxidedrug
The nitrous oxide group (GN2O) will receive 70% N2O in 30% O2 at the end of surgery.