CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 80 enrolled
Drug / intervention
Paclitaxel +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03423979
NCT03423979Phase 2Completed

Evaluation of Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter in the Treatment of Moderate-to-Severe Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Urotronic Inc.·interventional·Posted Feb 6, 2018·Updated Nov 26, 2025

In Brief

A Phase 2 clinical trial evaluating Optilume™ BPH Prostatic DCB Dilation Catheter and Paclitaxel for Benign Prostatic Hyperplasia and Benign Prostatic Hypertrophy. Completed, enrolled 80 participants across 5 sites in 2 countries.

Detailed Summary

A prospective, non-randomized study. The subjects will be enrolled and treated with the Optilume BPH Prostatic DCB Dilation Catheter System at up to 8 clinical sites. The post-treatment follow-up visit can be up to 5 years. The objective of the study is to evaluate the safety and efficacy of the Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter System in the treatment of BPH.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesDominican Republic, Panama
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedFeb 6, 2018
Enrollment StartDec 19, 2017
Primary CompletionJun 4, 2019
Study CompletionMay 25, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 8.4 years ago

Interventions

Optilume™ BPH Prostatic DCB Dilation Catheterdevice

BPH Prostatic DCB treatment - The Optilume BPH Prostatic DCB Dilation Catheter System should be prepared per the Instructions for Use (IFU).

Paclitaxeldrug

paclitaxel will release to adjacent tissue after the balloon inflated in the urethra