CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 78 enrolled
Drug / intervention
High-flow nasal cannuladevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03430206
NCT03430206N/ACompleted
CompareCT.gov

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Stanford University·interventional·Posted Feb 12, 2018·Updated Aug 6, 2020

In Brief

A clinical study evaluating High-flow nasal cannula for Oxygen Deficiency and 3 related conditions. Completed, enrolled 78 participants across 1 site.

Detailed Summary

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can safely prevent desaturation events in children under anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedFeb 12, 2018
Enrollment StartFeb 21, 2018
Primary CompletionOct 2, 2018
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 8.4 years ago

Interventions

High-flow nasal cannuladevice

While applied, the cannula will deliver high-flow rate oxygen, air, or a mixture of variable oxygen concentration (21-100%) depending on the surgical conditions and requirements. The rate will be set at 2L/kg/min with a maximum of 70L/min. This will be only for the duration of the surgery or procedure.