CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 283 enrolled
Drug / intervention
romosozumab HCP administration with PFS +1 moredrug
Likely dose
romosozumab HCP administration with PFS 210 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03432533
NCT03432533Phase 3Completed

A Randomized, Multicenter, Open-label, Parallel Group Study in Postmenopausal Women With Osteoporosis to Evaluate the Noninferiority of Subject-administered Romosozumab Via Autoinjector/Pen vs Healthcare Provider-administered Romosozumab Via Prefilled Syringe

Amgen·interventional·Posted Feb 14, 2018·Updated Nov 23, 2020

In Brief

A Phase 3 clinical trial evaluating romosozumab HCP administration with PFS and romosozumab self-administration with AI/Pen for Post-Menopausal Osteoporosis. Completed, enrolled 283 participants across 46 sites in 3 countries.

Detailed Summary

To evaluate the noninferiority of a 6-month treatment with 210 mg romosozumab at 90 mg/mL administered subcutaneously (SC) once a month (QM) in postmenopausal women with osteoporosis either by healthcare provider (HCP) administration with prefilled syringe (PFS) or by subject self-administration with autoinjector/pen (AI/Pen)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPoland, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedFeb 14, 2018
Enrollment StartFeb 6, 2018
Primary CompletionApr 11, 2019
Study CompletionJan 8, 2020
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 8.4 years ago

Interventions

romosozumab HCP administration with PFSdrug

210 mg romosozumab SC QM by HCP administration with 2 PFS

romosozumab self-administration with AI/Pendevice

210 mg romosozumab SC QM by self-administration with 2 AI/Pens