CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 21 enrolled
Drug / intervention
Nitrous Oxide Gas for Inhalationdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03435055
NCT03435055Phase 4Completed
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Network-Level Effects of Nitrous Oxide in the Human Brain

University of Michigan·interventional·Posted Feb 15, 2018·Updated Nov 30, 2021

In Brief

A Phase 4 clinical trial evaluating Nitrous Oxide Gas for Inhalation for Healthy. Completed, enrolled 21 participants across 1 site.

Detailed Summary

The purpose of this study is to understand how a commonly used drug, nitrous oxide, acts on the brain to reduce pain. Nitrous oxide is commonly used in anesthesiology but there is limited knowledge on how this drug affects functional networks in the brain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedFeb 15, 2018
Enrollment StartJul 21, 2017
Primary CompletionOct 11, 2019
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 8.4 years ago

Interventions

Nitrous Oxide Gas for Inhalationdrug

Each volunteer will participate in one scanning visit in which simultaneous functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) data will be collected wherein they receive placebo (20 minutes) followed by inhaled nitrous oxide at subanesthetic levels (35% inhaled concentration) over 40 minutes.