CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 60 enrolled
Drug / intervention
Cisticid +1 moredrug
Likely dose
Cisticid 1200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03437447
NCT03437447Phase 1Completed

A Phase I, Open-label, Randomized, Three-period, Crossover, Partial Replicated, Reference-scaled, Single Center Trial to Assess the Bioequivalence of a Single Oral Dose of 1200 mg of the New Cisticid 600 mg Tablet Formulation Versus Comparator Biltricide in Healthy Male Volunteers

Merck KGaA, Darmstadt, Germany·interventional·Posted Feb 19, 2018·Updated Sep 18, 2019

In Brief

A Phase 1 clinical trial evaluating Cisticid and Biltricide for Healthy. Completed, enrolled 60 participants across 1 site.

Detailed Summary

The purpose of this trial is to assess the bioequivalence (BE) of new 600 milligram (mg) Cisticid tablet (Test) versus 600 mg Biltricide tablets (Reference) at a dose of 1200 mg in healthy male participants. Praziquantel (PZQ) is the active ingredient for Cisticid and Biltricide tablets.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesMexico
Collaborators--

Timeline

Phase 1CompletedFinished
201820192020202120222023202420252026
First PostedFeb 19, 2018
Enrollment StartJun 18, 2018
Primary CompletionJul 6, 2018
TodayJul 2, 2026
Enrollment to primary: 18 daysPosted 8.4 years ago

Interventions

Cisticiddrug

Participants received single oral dose of 1200 mg (two 600 mg tablets) Cisticid (Test) on Day 1 (Treatment Period 1) or Day 8 (Treatment Period 2) or Day 15 (Treatment Period 3).

Biltricidedrug

Participants received 600 mg of Biltricide (Reference) tablet at a dose of 1200 mg on either Day 1 (Treatment Period 1) or Day 8 (Treatment Period 2).