CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 7,418 enrolled
Drug / intervention
Silver Diamine Fluoride +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03442309
NCT03442309N/ACompleted
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Silver Diamine Fluoride Versus Therapeutic Sealants for the Arrest and Prevention of Dental Caries in Low-income Minority Children

NYU College of Dentistry·interventional·Posted Feb 22, 2018·Updated Feb 26, 2025

In Brief

A clinical study evaluating Silver Diamine Fluoride, Fluoride Varnishes, and 1 other intervention for Dental Caries and Quality of Life. Completed, enrolled 7,418 participants across 1 site.

Detailed Summary

Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries. The aim of the proposed study is to compare the benefit of silver diamine fluoride (SDF) and fluoride varnish versus fluoride varnish and glass ionomer sealants. This study is a five-year, cluster randomized, pragmatic controlled trial conducted in public elementary schools in New York City.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Caries, Quality of Life
CountriesUnited States
CollaboratorsPatient-Centered Outcomes Research Institute, Boston University, New York City Department of Health and Mental Hygiene

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedFeb 22, 2018
Enrollment StartFeb 1, 2019
Primary CompletionJun 30, 2023
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 8.4 years ago

Interventions

Silver Diamine Fluoridedevice

Silver diamine fluoride (SDF)

Fluoride Varnishesdevice

Fluoride varnish (FV)

Glass Ionomerdevice

Glass Ionomer Sealants (GC Fuji IX)