At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Reduction of Cardiac Steatosis and Improvement of Diastolic Function by Modulating Metabolic Health in Obese Individuals
In Brief
A clinical study evaluating High intensity exercise, Omega-3 fish oil, and 2 other interventions for Obesity and 2 related conditions. Completed, enrolled 80 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in conjunction with daily oral administration of omega-3 poly-unsaturated fatty acids will lead to reduction in visceral adiposity, regression of myocardial triglyceride levels and improvements in cardiac diastolic and vascular function.
Study Details
Timeline
Interventions
Subjects will be randomized to the exercise groups will undergo 1 year aerobic exercise training comprised of high intensity exercise sessions 2-3 days per week. Sessions will be supervised remotely via heart rate monitors.
Subjects randomized to omega-3 fatty acids will take 2 grams total of omega-3 per day for 1 year.
Subjects randomized to yoga will undergo yoga training as a control to those randomized to high intensity aerobic exercise.
Subjects randomized to receive olive oil placebo will take 1 gram total of olive oil capsule per day.