At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Antibiotic Prophylaxis in Ragged Placental Membranes: A Prospective, Multicenter, Randomized Trial
In Brief
A clinical study evaluating Prophylactic antibiotics and No prophylaxis (Amox-clav withheld) for Endometritis Postpartum and 2 related conditions. Completed, enrolled 716 participants.
Detailed Summary
In some centres, women are routinely given a course of antibiotics postnatally if ragged placental membranes were present at delivery. The investigators examined the necessity such an intervention.
Study Details
Timeline
Interventions
Amox-clav given to eligible women as per existing protocol, which is 625mg three times a day, for a week
Withholding Amox-clav, which is the current local practice for women with ragged placental membranes. This was replaced with appropriate counselling on signs and symptoms of endometritis, when and where women should present if the symptoms above occur. A follow up phone call was performed at 2 weeks and 6 weeks postpartum to ascertain well-being of patients