CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 33 enrolled
Drug / intervention
Recombinant Human Plasma Gelsolin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03466073
NCT03466073Phase 2Completed

A Double-blind, Placebo-controlled, Dose-escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Plasma Gelsolin Added to Standard of Care in Subjects Hospitalized for Acute Community-acquired Pneumonia

BioAegis Therapeutics Inc.·interventional·Posted Mar 15, 2018·Updated Jan 27, 2020

In Brief

A Phase 2 clinical trial evaluating Recombinant Human Plasma Gelsolin and Normal Saline Placebo for Community-acquired Pneumonia. Completed, enrolled 33 participants across 8 sites in 2 countries.

Detailed Summary

A Phase 1b/2a, Double-blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Plasma gelsolin (rhu-pGSN) Added to Standard of Care in Subjects Hospitalized for Acute Community-acquired Pneumonia (CAP)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Georgia
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMar 15, 2018
Enrollment StartAug 28, 2018
Primary CompletionApr 2, 2019
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 8.3 years ago

Interventions

Recombinant Human Plasma Gelsolindrug

Recombinant human plasma gelsolin lyophilized for reconstitution, reconstituted in sterile water

Normal Saline Placeboother

Normal saline in volume equivalent to drug