CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 8 enrolled
Drug / intervention
Insulin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03469492
NCT03469492Early Ph 1Completed

Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose: an Intervention Study

Yale University·interventional·Posted Mar 19, 2018·Updated Feb 5, 2024

In Brief

A Early Phase 1 clinical trial evaluating Insulin, exercise, and 1 other intervention for Hyperglycaemia (Diabetic). Completed, enrolled 8 participants across 1 site.

Detailed Summary

To investigate whether longer-term improvement of glycemic control in poorly controlled diabetes patients with a 12-week intensified insulin treatment regimen will lead to decreased polyol pathway activity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Early Ph 1CompletedFinished
201820192020202120222023202420252026
First PostedMar 19, 2018
Enrollment StartJan 18, 2018
Primary CompletionMar 20, 2020
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 8.3 years ago

Interventions

Insulindrug

Insulin regimens will be adjusted on a weekly basis as needed to achieve a target blood glucose level.

exercisebehavioral

Exercise in accordance to the guidelines established by the American Diabetes Association.

Dietary counselingdietary

Dietary counseling in accordance to the guidelines established by the American Diabetes Association.