CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
SAPIEN 3 Ultra Delivery System with the SAPIEN 3 Ultra THVdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03471065
NCT03471065N/ACompleted

A Prospective, Single-arm, Multicenter Study of the SAPIEN 3 Ultra System in Intermediate Risk Patients With Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement

Edwards Lifesciences·interventional·Posted Mar 20, 2018·Updated May 18, 2025

In Brief

A clinical study evaluating SAPIEN 3 Ultra Delivery System with the SAPIEN 3 Ultra THV for Aortic Valve Stenosis. Completed, enrolled 100 participants across 6 sites in 2 countries.

Detailed Summary

This study will confirm the procedural safety and performance of the SAPIEN 3 Ultra System in subjects with severe, calcific AS who are at intermediate operative risk for standard aortic valve replacement.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United Kingdom
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMar 20, 2018
Enrollment StartJun 1, 2018
Primary CompletionDec 23, 2019
Study CompletionJan 21, 2025
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 8.3 years ago

Interventions

SAPIEN 3 Ultra Delivery System with the SAPIEN 3 Ultra THVdevice

Patients will be implanted with the SAPIEN 3 Ultra THV (20, 23 and 26 mm) or SAPIEN 3 THV (29 mm) using the SAPIEN 3 Ultra Delivery System.