CI

At a glance

ClinicalIndex Comparison Record
Phase 4Active· 120 target
Drug / intervention
Contrast-Enhanced Ultrasound using Lumasondrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03473249
NCT03473249Phase 4ActiveOn TrackUpdated 6mo ago

Clinical Effectiveness of Contrast-Enhanced Ultrasound in the Evaluation of Blunt Abdominal Trauma in Young Children

Children's Hospital of Philadelphia·interventional·Posted Mar 22, 2018·Updated Dec 24, 2025

In Brief

A Phase 4 clinical trial evaluating Contrast-Enhanced Ultrasound using Lumason for Abdominal Injuries and 3 related conditions. Active but no longer recruiting, targeting 120 participants across 1 site.

Detailed Summary

The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma. The primary objective in this study is to determine the sensitivity and specificity of contrast-enhanced ultrasound (CEUS) compared to abdominal Computed Tomography (CT) in the detection of abdominal solid organ injury in young children \< 8 years of age with concern for blunt abdominal trauma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4Active
2018201920202021202220232024202520262027
First PostedMar 22, 2018
Enrollment StartMay 9, 2018
Primary CompletionDec 1, 2026
TodayJul 2, 2026
Enrollment to primary: 8.6 yearsPosted 8.3 years agoPrimary completion in 5 months

Interventions

Contrast-Enhanced Ultrasound using Lumasondrug

Subjects will undergo a contrast enhanced ultrasound (CEUS) during which a standard greyscale abdominal ultrasound is performed first followed by injection of intravenous contrast with Lumason, and completion of contrast-enhanced ultrasound