At a glance
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Tranexamic Acid for the Prevention of Postpartum Bleeding in Women With Anaemia: an International, Randomised, Double-blind, Placebo Controlled Trial.
In Brief
A Phase 3 clinical trial evaluating Tranexamic Acid and Placebo for Intrapartum - Moderate and Severe Anaemia. Completed, enrolled 15,068 participants across 41 sites in 4 countries.
Detailed Summary
Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries. When given within three hours of birth, tranexamic acid reduces deaths due to bleeding in women with PPH by almost one third. However, for many women, treatment of PPH is too late to prevent death and severe morbidities. Over one-third of pregnant women in the world are anaemic and many are severely anaemic. We now want to do the WOMAN-2 trial to see if giving tranexamic acid can prevent PPH and other severe outcomes in women with moderate and severe anaemia.
Study Details
Timeline
Interventions
Ampoules and packaging for both arms will be identical in appearance.
Ampoules and packaging for both arms will be identical in appearance.