CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,116 enrolled
Drug / intervention
Enhanced Couple HIV Testing and Counselingbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03477279
NCT03477279N/ACompleted

Developing and Assessing a Male Engagement Intervention in Option B+ in Malawi: A Randomized Controlled Trial in Lilongwe

University of North Carolina, Chapel Hill·interventional·Posted Mar 26, 2018·Updated Jun 24, 2021

In Brief

A clinical study evaluating Enhanced Couple HIV Testing and Counseling for Hiv. Completed, enrolled 1,116 participants across 1 site.

Detailed Summary

There is promising evidence that couple-based approaches within Malawi's Option B+ prevention of mother to child transmission program could address help address 1) poor male engagement in the HIV continuum of care, 2) low male adoption of biomedical HIV prevention approaches, 3) sub-optimal female engagement in the continuum of care, and 4) poor or uncertain infant outcomes. Our team has developed an intervention to address these challenges, and will conduct a randomized controlled trial (N=500 couples) to assess intervention effectiveness at one year. Women with recent HIV infections enrolled in this trial will be compared against a cohort of 350 HIV-uninfected women to explore predictors of HIV acquisition in pregnancy in Malawi.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHiv
CountriesMalawi

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMar 26, 2018
Enrollment StartSep 25, 2017
Primary CompletionJul 21, 2020
Study CompletionSep 30, 2020
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 8.3 years ago

Interventions

Enhanced Couple HIV Testing and Counselingbehavioral

Participants are provided study-specific partner referral cards and encouraged to bring male partners to antenatal care for a male engagement intervention. Those who do not present on their own are then traced. Couples will receive three enhanced couple counseling sessions that include: pre-test counseling, return of joint results, and post-test counseling. HIV-infected men will be able to initiate cART at the antenatal clinic and the couple will be offered condoms from the HTC counselor. Between sessions, couple members can pick up condoms and cART for one another.