At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 20 enrolled / 20 target
Drug / intervention
Ze 117 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Drug Cocktail Interaction Study to Investigate the Effect of St. John's Wort Dry Extract Ze 117 on Several Cytochrome P450 Enzymes and on Transporter P-Glycoprotein in Healthy Volunteers
In Brief
A Phase 1 clinical trial evaluating Ze 117 and Probe drug cocktail for Drug Interaction Study. Completed, enrolled 20 participants across 1 site.
Signals
Enrollment appears stalled
Detailed Summary
This Study evaluates the Effect of St. John's Wort dry Extract Ze 117 on Several Cytochrome P450 Enzymes and on Transporter P-Glycoprotein in Healthy Volunteers.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDrug Interaction Study
CountriesGermany
Collaborators--
Timeline
Phase 1CompletedFinished
201820192020202120222023202420252026
Enrollment StartFeb 2018
First PostedMar 2018
Primary CompletionMay 2018
Study CompletionJun 2018
TodayJul 2026
First PostedMar 29, 2018
Enrollment StartFeb 5, 2018
Primary CompletionMay 17, 2018
Study CompletionJun 23, 2018
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 8.3 years ago
Arms & Interventions
Probe drug cocktail / Ze 117experimental
One-sequence, Probe drug cocktail alone and in combination with Ze 117.
Drug: Ze 117Drug: Probe drug cocktail
Interventions
Ze 117drug
Subjects will be hospitalized to receive a probe drug cocktail alone and in combination with Ze 117.
Probe drug cocktaildrug
Subjects will be hospitalized to receive a probe drug cocktail alone and in combination with Ze 117.