CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 37 enrolled
Drug / intervention
Metoprolol Succinate 25 MG +2 moredrug
Likely dose
Metoprolol Succinate 25 MGfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03488719
NCT03488719Phase 1Completed
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A Phase 1 Study to Examine Pharmacodynamic Interaction Between Tesofensine and Metoprolol on 24-hours Mean Heart Rate

Saniona·interventional·Posted Apr 5, 2018·Updated Feb 9, 2024

In Brief

A Phase 1 clinical trial evaluating Metoprolol Succinate 25 MG, Metoprolol Succinate 50 MG, and 1 other intervention for Phase 1. Completed, enrolled 37 participants across 1 site.

Detailed Summary

A Phase 1 Study to Examine Pharmacodynamic Interaction Between Tesofensine and Metoprolol on 24-hours Mean Heart Rate

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPhase 1
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedApr 5, 2018
Enrollment StartJul 11, 2018
Primary CompletionJun 6, 2019
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 8.2 years ago

Interventions

Metoprolol Succinate 25 MGdrug

A single dose of 25 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21 approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.

Metoprolol Succinate 50 MGdrug

A single dose of 50 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21 approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.

Metoprolol Succinate 100 MGdrug

A single dose of 100 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21, approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.