At a glance
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Prospective Multicenter Observational Cohort Study of Comparative Effectiveness of Disease-modifying Treatments for Myasthenia Gravis
In Brief
An observational study evaluating Mycophenolate Mofetil and Azathioprine for Neurological Disorder and Autoimmune Diseases. Completed, enrolled 82 participants across 19 sites in 2 countries.
Signals
Detailed Summary
This study is designed to address the evidence gaps in a real-world setting and help patients with MG choose treatments that are best suited to them. It is a prospective, multicenter observational cohort study of comparative effectiveness of MG treatments, with a patient-centered primary outcome measure, to guide clinicians, patients and payers regarding the choice of treatment options for this chronic and serious disease. Primary: To compare the effectiveness of azathioprine (AZT) and mycophenolate mofetil (MMF). Secondary: To compare the outcomes in patients receiving an adequate dose and duration of AZT or MMF over the 2-3 year study period, vs. patients not receiving adequate doses and duration of these agents
Study Details
Timeline
Arms & Interventions
Patients with MG who are receiving azathioprine as part of routine clinical care
Patients with MG who are receiving mycophenolate mofetil as part of routine clinical care
Interventions
oral tablets
oral tablet