CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 94 enrolled
Drug / intervention
Nicotine patch +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03492463
NCT03492463Phase 2Completed
CompareCT.gov

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products

Duke University·interventional·Posted Apr 10, 2018·Updated Feb 8, 2023

In Brief

A Phase 2 clinical trial evaluating Nicotine patch, Placebo patch, and 2 other interventions for Nicotine Dependence, Cigarettes. Completed, enrolled 94 participants across 1 site.

Detailed Summary

This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNicotine Dependence, Cigarettes
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedApr 10, 2018
Enrollment StartAug 6, 2018
Primary CompletionMay 31, 2021
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 8.2 years ago

Interventions

Nicotine patchdrug

Participants will wear the nicotine patch daily while switching from cigarette use to use of e-cigarettes for eight weeks.

Placebo patchother

Participants will wear the placebo patch daily while switching from cigarette use to use of e-cigarettes for eight weeks.

E-cigarettesother

Participants will use e-cigarettes containing nicotine while switching from cigarette use to use of e-cigarettes for eight weeks.

Non-nicotine e-cigarettesother

Participants will use e-cigarettes not containing nicotine while switching from cigarette use to use of e-cigarettes for eight weeks.