CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 1,021 enrolled
Drug / intervention
rMenB+OMV NZ vaccine +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03493919
NCT03493919Phase 4Completed

A Sourcing Study to Collect Human Biological (Serum) Samples From Healthy Adults

GlaxoSmithKline·interventional·Posted Apr 11, 2018·Updated Jul 17, 2023

In Brief

A Phase 4 clinical trial evaluating rMenB+OMV NZ vaccine and Meningococcal Groups A, C, W and Y Conjugate Vaccine (MenACWY) for Meningitis, Meningococcal. Completed, enrolled 1,021 participants across 6 sites in 2 countries.

Detailed Summary

The purpose of this study was to collect large volumes of matched pairs of pre- and post-vaccination sera from healthy subjects who administered GlaxoSmithKline (GSK) Biologicals' vaccine against meningitis- MenACWY vaccine (Menveo) or rMenB+OMV NZ vaccine (Bexsero), which serves for the development, qualification, validation, and maintenance of immunological assays which supports the preclinical research activities and clinical development of GSK Biologicals' vaccines. The safety of the subjects given one of the two vaccines (Bexsero or Menveo), as per the recommended dosage and schedule were assessed during their participation in the study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Germany
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedApr 11, 2018
Enrollment StartMar 8, 2018
Primary CompletionMay 27, 2022
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 8.2 years ago

Interventions

rMenB+OMV NZ vaccinebiological

Two doses of rMenB+OMV NZ vaccine were administered intramuscularly at Day 1 and Day 61.

Meningococcal Groups A, C, W and Y Conjugate Vaccine (MenACWY)biological

One dose of MenACWY vaccine were administered intramuscularly at Day 1.