At a glance
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Post-chemotherapy Symptom Management: Testing Intervention Sequences in a SMART Design
In Brief
A clinical study evaluating Start with SMSH+TIPC and Start with SMSH alone for Cancer. Completed, enrolled 498 participants across 2 sites.
Detailed Summary
Survivors of solid tumors (N=451) who completed curative intent chemotherapy for a solid tumor within the past 2 years were interviewed at baseline and stratified as high or low need for symptom management based on comorbidity and depressive symptoms. High need survivors were randomized initially to the 12-week Symptom Management and Survivorship Handbook (SMSH, N=282) or 12-week SMSH Telephone Interpersonal Counseling (TIPC, N=93) added during weeks 1-8. After 4 weeks of the SMSH alone, non-responders on depression were re-randomized to continue with SMSH alone (N=30) or add TIPC (N=31).
Study Details
Timeline
Interventions
See arm/group descriptions
See arm/group descriptions