CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
Lpc-37 +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03494725
NCT03494725N/ACompleted
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Proof-of-Concept "Stress & Anxiety Dampening Effects of Lpc-37"

Daacro·interventional·Posted Apr 11, 2018·Updated Feb 25, 2021

In Brief

A clinical study evaluating Lpc-37 and Placebo for Healthy and Stress, Psychological. Completed, enrolled 120 participants across 1 site.

Detailed Summary

The aim of this study is to assess whether a 5 week intake of a probiotic (Lpc-37) can modulate stress and anxiety experienced by healthy subjects during and after an acute stressor compared to placebo. To measure stress and anxiety, markers of the hypothalamic-pituitary-adrenal (HPA) axis activity and questionnaires will be assessed before, during and after the Trier Social Stress Test (TSST). The results of this study indicate if the chosen study design is suitable to discover stress-related effects of probiotics.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy, Stress, Psychological
CountriesGermany
CollaboratorsDuPont Nutrition and Health

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedApr 11, 2018
Enrollment StartApr 10, 2018
Primary CompletionOct 9, 2018
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 8.2 years ago

Interventions

Lpc-37dietary

Lacticaseibacillus paracasei Lpc-37 at 1.75 x 10\^10 colony forming units (CFU) per day, microcrystalline cellulose, magnesium stearate, silicon dioxide

Placebodietary

microcrystalline cellulose, magnesium stearate, silicon dioxide