At a glance
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Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan Africa
In Brief
A clinical study evaluating Incentivization based on high adherence, Incentivization based on timely clinic visit, and 3 other interventions for HIV/AIDS. Completed, enrolled 331 participants across 1 site.
Detailed Summary
This study will implement an intervention in a two-year randomized controlled trial (RCT) to establish efficacy on viral suppression as a biological endpoint, compare the effectiveness of two different modes of implementation (including one entirely based on readily available clinic data), and investigate cost-effectiveness. Participants in the first intervention group (T1, n=110) will be eligible for small lottery prizes based on timely clinic visits, and qualify for an annual lottery conditional if demonstrating viral suppression; those in the second group (T2, n=110) will draw prizes conditional on electronically measured adherence at each clinic visit, and also participate in an annual lottery that is conditional on high adherence throughout the year. The control group (n=110) will receive the usual standard of care. Assessments will be conducted at baseline and then every six months. Primary outcomes are undetectable viral load and electronically measured adherence.
Study Details
Timeline
Interventions
When a participant comes for a regular clinic visit, s/he will have the MEMS data extracted, and if adherence over the previous month \>=90%, will participate in a prize drawing.
When a participant comes for a regular clinic visit on the day s/he is scheduled, s/he will participate in a prize drawing.
Participants will have a chance to take part in an annual drawing where eligibility is based on the average adherence during that year.
Participants will have a chance to take part in an annual drawing where eligibility is based on showing viral suppression.
Those participants not showing viral suppression at month 12 will be randomized in a 1:1 fashion to receive an additional intervention component or continue receiving the same intervention arm as in Year 1.