CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 422 enrolled
Drug / intervention
Experimental Oralbalance Moisturizing Gel +3 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03494985
NCT03494985N/ACompleted

A Clinical Study to Evaluate the Efficacy of an Experimental Oralbalance Gel, Oral Rinse and Spray Versus Water

GlaxoSmithKline·interventional·Posted Apr 11, 2018·Updated Sep 26, 2018

In Brief

A clinical study evaluating Experimental Oralbalance Moisturizing Gel, Biotene Original Oral Rinse, and 2 other interventions for Xerostomia. Completed, enrolled 422 participants.

Detailed Summary

This study assessed the efficacy of three dry mouth products (including an experimental Oralbalance gel, oral rinse, and moisturizing spray) to relieve the feeling of dry mouth compared to water, in dry mouth population over a period of 28 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsXerostomia
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedApr 11, 2018
Enrollment StartSep 17, 2013
Primary CompletionJan 10, 2014
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 8.2 years ago

Interventions

Experimental Oralbalance Moisturizing Geldevice

Participants placed approximately a half inch length of the gel onto the tongue and spread thoroughly using their tongue. Participants used their assigned treatment products for 28 days as specified on their diary/instructions, at least twice and no more than 5 times daily.

Biotene Original Oral Rinsedevice

Participants rinsed their mouth with 15 milliliters (mL) of oral rinse for 30 seconds and spat out. Participants used their assigned treatment products for 28 days as specified on their diary/instructions, at least twice and no more than 5 times daily.

Biotene Moisturizing Mouth Spraydevice

Participants sprayed one jet directly into their mouth. Participants used their assigned treatment products for 28 days as specified on their diary/instructions, at least twice and no more than 5 times daily.

Waterother

Participants were allowed to take only one measured sip of water (15 mL) 30 minutes before the supervised product use. After the supervised treatment at the site, participants assigned to the water only treatment were allowed to sip water as often as required.