CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 1,748 enrolled
Drug / intervention
Cognitive Bias Modification - Interpretation training +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03498651
NCT03498651Phase 2Completed

Effectiveness of Interpretation of Training to Reduce Anxiety: Evaluating Technology-based Delivery Models and Methods to Reduce Attrition

University of Virginia·interventional·Posted Apr 17, 2018·Updated Feb 19, 2025

In Brief

A Phase 2 clinical trial evaluating Cognitive Bias Modification - Interpretation training, Coaching, and 1 other intervention for Anxiety. Completed, enrolled 1,748 participants across 1 site.

Detailed Summary

The project aims to compare effectiveness and target engagement of CBM-I delivered via computer vs. mobile phone, and test if adding minimal human contact for participants at risk of dropout improves retention and outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedApr 17, 2018
Enrollment StartJan 20, 2019
Primary CompletionDec 3, 2020
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 8.2 years ago

Interventions

Cognitive Bias Modification - Interpretation trainingbehavioral

Training involves presenting participants with brief scenarios that introduce an ambiguous potential threat. Critically, the ambiguity regarding how the situation is resolved remains until the last word of the scenario, which is presented as a word fragment that the participant must solve, which will typically then assign a benign (rather than threatening) meaning to the scenario.

Coachingbehavioral

Participants identified as high risk for attrition will receive low-intensity coaching, which includes a mix of brief phone calls, texts, and/or emails with a trained member of the study team to help address challenges with adherence to and application of the training.

Online psychoeducation about anxietybehavioral

Participants will review webpages that describe information about symptoms and causes of anxiety, including the nature of biased thinking in anxiety.