CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 90 enrolled
Drug / intervention
anesthesiaprocedure
Likely dose
Not stated in record
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Search/NCT03499132
NCT03499132N/ACompleted

Influence of Different Anesthetic Procedures on Sleep Disorder Breathing in Adult Patients Undergoing Elective Surgery

St. Anne's University Hospital Brno, Czech Republic·observational·Posted Apr 17, 2018·Updated Mar 17, 2020

In Brief

An observational study evaluating anesthesia for Obstructive Sleep Apnea. Completed, enrolled 90 participants across 1 site.

Detailed Summary

Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications. These complications are caused not only by the OSA itself, but also by exacerbations of this syndrome during the perioperative period (1). Benzodiazepines, volatile anesthetics and opioids may lead to lower hypoxia and hypercapnia sensitivity and may cause respiratory depression (2-5). Therefore, preference of neuraxial blockades and avoidance of opioids has been suggested for patients with OSA (6). However, there is still lack of evidence to evaluate the effects of various anesthesia procedures on OSA (6,7). We hypothesize different anesthetic procedures will have different effect on OSA exacerbations in the postoperative period. Accordingly, the aim of this study is to compare the number of sleep disordered breathing episodes in the postoperative period in patients with different anesthetic procedures.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesCzechia
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedApr 17, 2018
Enrollment StartMar 1, 2018
Primary CompletionDec 31, 2019
Study CompletionMar 1, 2020
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 8.2 years ago

Interventions

anesthesiaprocedure

Different anesthetic procedures