CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 43 enrolled
Drug / intervention
Isatuximab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03499808
NCT03499808Phase 2Completed

A Phase II Study of Isatuximab (SAR650984) (NSC-795145) for Patients With Previously Treated AL Amyloidosis

SWOG Cancer Research Network·interventional·Posted Apr 17, 2018·Updated Sep 9, 2025

In Brief

A Phase 2 clinical trial evaluating Isatuximab and Laboratory Biomarker Analysis for Amorphous, Eosinophilic, and Acellular Deposit and 12 related conditions. Completed, enrolled 43 participants across 345 sites.

Detailed Summary

This phase II trial studies how well isatuximab works in treating patients with primary amyloidosis that has come back or does not respond to treatment. Monoclonal antibodies, such as isatuximab, may interfere with the ability of cancer cells to grow and spread.

Study Details

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedApr 17, 2018
Enrollment StartJun 6, 2018
Primary CompletionAug 30, 2023
Study CompletionSep 19, 2023
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 8.2 years ago

Interventions

Isatuximabbiological

Given IV

Laboratory Biomarker Analysisother

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