CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 127 enrolled
Drug / intervention
Optilume Drug Coated Balloon (DCB) +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03499964
NCT03499964N/AActive

ROBUST III - Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease - A Randomized Control Trial

Urotronic Inc.·interventional·Posted Apr 17, 2018·Updated May 19, 2026

In Brief

A clinical study evaluating Optilume Drug Coated Balloon (DCB) and Control Treatment for Urethral Stricture. Active but no longer recruiting, targeting 127 participants across 22 sites in 2 countries.

Detailed Summary

ROBUST III is a prospective, multi-center, randomized controlled adaptive sample size clinical trial to establish the safety and effectiveness for the Optilume Stricture Drug Coated Balloon (DCB).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States

Timeline

N/AActive
20192020202120222023202420252026
First PostedApr 17, 2018
Enrollment StartJun 22, 2018
Primary CompletionDec 10, 2020
Study CompletionAug 1, 2026
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 8.2 years ago

Interventions

Optilume Drug Coated Balloon (DCB)device

The Optilume Drug Coated Balloon (DCB) is a guidewire compatible catheter with a tapered atraumatic tip. The distal end of the catheter has an inflatable balloon coated with a proprietary coating containing the drug paclitaxel that facilitates the drug's transfer to the urethral wall upon inflation.

Control Treatmentdevice

A control subject may be dilated with either a rod, uncoated balloon or DVIU until the desired result is reached, based on standard of care for the clinical site and treating physician