At a glance
ClinicalIndex Comparison RecordN/ACompleted· 14 enrolled
Drug / intervention
Metronome-paced tachypnea +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Dynamic Hyperinflation on the Left-ventricular Diastolic Function in Healthy Male Subjects
In Brief
A clinical study evaluating Metronome-paced tachypnea and Expiratory-stenosis breathing for Pulmonary Disease, Chronic Obstructive. Completed, enrolled 14 participants across 1 site.
Detailed Summary
The aim of this study is to identify whether actively induced dynamic hyperinflation can cause left-ventricular diastolic dysfunction in healthy male subjects in order to explore the mechanisms of developing cardiac dysfunctions in patients with COPD.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPulmonary Disease, Chronic Obstructive
CountriesAustria
Collaborators--
Timeline
N/ACompletedFinished
2017201820192020202120222023202420252026
Enrollment StartNov 2016
Primary CompletionSep 2017
Study CompletionSep 2017
First PostedApr 2018
TodayJul 2026
First PostedApr 18, 2018
Enrollment StartNov 1, 2016
Primary CompletionSep 1, 2017
Study CompletionSep 29, 2017
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 8.2 years ago
Interventions
Metronome-paced tachypneaprocedure
three cycles: breathing frequency (BF) - 40/min, inspiration : expiration (I : E) - 1 : 1; BF - 40/min, I : E - 1 : 2; BF - 30/min, I : E - 1 : 2
Expiratory-stenosis breathingprocedure
three cycles: BF - /min, I : E - 1 : 3; stenosis: 3mm; 2mm; 1,5mm