CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 544 enrolled
Drug / intervention
TV-46000 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03503318
NCT03503318Phase 3Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Risperidone Extended-Release Injectable Suspension (TV-46000) for Subcutaneous Use as Maintenance Treatment in Adult and Adolescent Patients With Schizophrenia

Teva Branded Pharmaceutical Products R&D, Inc.·interventional·Posted Apr 19, 2018·Updated Mar 10, 2023

In Brief

A Phase 3 clinical trial evaluating TV-46000 and Placebo for Schizophrenia. Completed, enrolled 544 participants across 81 sites in 2 countries.

Detailed Summary

The purpose of the study is to evaluate the efficacy, safety, and tolerability of different dose regimens of TV-46000 administered subcutaneously (SC) as compared to placebo during maintenance treatment in adult and adolescent participants with schizophrenia. The study will include male and female participants, 13 to 65 years of age, who have a confirmed diagnosis of schizophrenia, are clinically stable, and are eligible for risperidone treatment

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSchizophrenia
CountriesBulgaria, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedApr 19, 2018
Enrollment StartApr 27, 2018
Primary CompletionSep 30, 2020
Study CompletionDec 3, 2020
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 8.2 years ago

Interventions

TV-46000drug

TV-46000 will be administered per dose and schedule specified in the arm.

Placebodrug

Placebo matching to TV-46000 will be administered per schedule specified in the arm.