CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Retimer +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03513848
NCT03513848N/ACompleted

Morning Light Treatment at Home to Reduce PTSD Symptoms

Rush University Medical Center·interventional·Posted May 2, 2018·Updated Oct 23, 2019

In Brief

A clinical study evaluating Retimer and Retimer placebo for PTSD. Completed, enrolled 15 participants across 1 site.

Detailed Summary

There is evidence that some of the circadian photoreceptors, the intrinsically photosensitive retinal ganglion cells (ipRGCs), project directly to the amygdala, an area of the brain implicated in PTSD. Thus, a self-administered morning light treatment at home (shifts clock earlier and stimulates ipRGCs) may be a potentially efficacious adjunctive strategy for reducing PTSD symptoms. This study will test a 4 week daily 1 hour morning light treatment (active vs placebo) in individuals with PTSD. Outcome measures include measures of PTSD and depression.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPTSD
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 2, 2018
Enrollment StartApr 1, 2016
Primary CompletionJun 27, 2018
Study CompletionJun 28, 2018
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 8.2 years ago

Interventions

Retimerdevice

The Retimer light device in this study is a commercially-available wearable light device. It permits ambulation while receiving light from LEDs positioned below the eyes. The LEDs emit green light (\~500nm, 230 µW/m2, 500 lux), close to the peak sensitivity of circadian photoreceptors.

Retimer placebodevice

The Retimer device has been dimmed to reduce the light intensity to a level that will not shift circadian timing.